Journal of Interdisciplinary Dentistry

: 2014  |  Volume : 4  |  Issue : 1  |  Page : 59-

An update on remineralization agents

Garima Malhotra 
 Department of Conservative Dentistry and Endodontics, ITS Dental College, Hospital and Research Center, Greater Noida, Uttar Pradesh, India

Correspondence Address:
Garima Malhotra
Department of Conservative Dentistry and Endodontics, ITS Dental College, Hospital and Research Center, Greater Noida, Uttar Pradesh

How to cite this article:
Malhotra G. An update on remineralization agents.J Interdiscip Dentistry 2014;4:59-59

How to cite this URL:
Malhotra G. An update on remineralization agents. J Interdiscip Dentistry [serial online] 2014 [cited 2022 Sep 30 ];4:59-59
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Dear Editor,

In the JID article (September-December 2013 issue) by Tyagi et al. remineralization agents were reviewed in the article titled, "an update on remineralizing agents." [1] The article is very informative and explains the natural phenomenon of enamel demineralization and remineralization, while discussing the clinical relevance of remineralizing products to contemporary dental practice.

Dental caries is the most widespread disease affecting all age groups. White spot lesion is the only reversible step in the progress of dental caries and remineralizing the white spot lesion by various remineralizing agents halts the progress of dental caries. Apart from the various remineralization agents discussed in this article, three recent techniques/agents could have been added to this article. These include the use of ion-exchange resins [2] as a remineralization agent and resin infiltration technique [3] and calcium carbonate carrier. [4]

Ion-exchange system provides a controlled release system, which supplies calcium, fluoride, phosphate, and zinc ions, to promote remineralization. A dentifrice containing a mixture of ion-exchange resins is evaluated by Torrado et al. [2] and concluded inclusion of calcium phosphate ion-exchange resins promotes remineralization.

In resin infiltration technique, low viscosity resin of type tri-ethylene glycol dimethacrylate with a sufficiently high (>200 cm/s) penetration coefficient is applied on the white spot lesion after acid etching with 15% hydrochloric acid gel for 2 min, which halts the progression of lesion.

In calcium carbonate carrier is complexed with arginine to form arginine bicarbonate, an amino acid complex, which is responsible for the long-term adhesion of the calcium particles with enamel or dentin surface aids in remineralization.


1Tyagi SP, Garg P, Sinha DJ, Singh UP. An update on remineralizing agents. J Interdiscip Dent 2013;3:151-8.
2Torrado A, Valiente M, Zhang W, Li Y, Muñoz CA. Remineralization potential of a new toothpaste formulation: An in vitro study. J Contemp Dent Pract 2004;5:18-30.
3Lasfargues JJ, Bonte E, Guerrieri A, Fezzani L. Minimal intervention dentistry: Part 6. Caries inhibition by resin infiltration. Br Dent J 2013;214:53-9.
4Goswami M, Saha S, Chaitra TR. Latest developments in non-fluoridated remineralizing technologies. J Indian Soc Pedod Prev Dent 2012;30:2-6.