J Interdiscip Dentistry
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Year : 2020  |  Volume : 10  |  Issue : 3  |  Page : 111-116

Effect of probiotics on Candida in diabetic and nondiabetic complete denture wearers – An In vivo study

1 Department of Prosthodontics and Crown and Bridge, JSS Dental College and Hospital, Mysore, Karnataka, India
2 Department of Microbiology, JSS Medical College and Hospital, Mysore, Karnataka, India
3 Department of Oral Pathology and Microbiology, Mamata Dental College, Khammam, Telengana, India

Correspondence Address:
Dr. Karteek Durbakula
Department of Oral Pathology and Microbiology, Mamata Dental College, Khammam, Telengana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jid.jid_49_20

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Aim: To evaluate the effectiveness of probiotics on Candida albicans in diabetic and nondiabetic complete denture wearers. Study Design: Twenty complete denture wearers with dentures aging more than 6 months were selected randomly and divided into two groups (controlled diabetic and nondiabetic) based on their blood glucose levels and medical history. Materials and Methods: Probiotics were prescribed for all the subjects for the duration of 30 days. Microbial swab was collected from their dentures at 0, 15th, and 30th days and incubated in Sabouraud's dextrose agar broth. C. albicans colony-forming units (CFU/ml) were counted. Statistical Analysis: The candidial CFUs were compared using statistical analyses such as descriptive statistics, paired samples t-test, independent samples t-test, and repeated-measures ANOVA test and P < 0.05 was considered as statistically significant. Results: C. albicans count reduced in both the groups during the usage of probiotics, but the reduction was more in controlled diabetic subjects which showed statistically significant results. Conclusion: Probiotics can be used as an alternative therapy for the management of oral candidiasis in denture wearers particularly in controlled diabetic patients.

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