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Table of Contents
LETTER TO EDITOR
Year : 2018  |  Volume : 8  |  Issue : 1  |  Page : 41

Refractory Mucormycosis: A Possible Cause for Maxillary Necrosis


Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

Date of Web Publication5-Mar-2018

Correspondence Address:
Mahmood Dhahir Al-Mendalawi
Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, P. O. Box: 55302, Baghdad Post Office, Baghdad
Iraq
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jid.jid_96_17

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How to cite this article:
Al-Mendalawi MD. Refractory Mucormycosis: A Possible Cause for Maxillary Necrosis. J Interdiscip Dentistry 2018;8:41

How to cite this URL:
Al-Mendalawi MD. Refractory Mucormycosis: A Possible Cause for Maxillary Necrosis. J Interdiscip Dentistry [serial online] 2018 [cited 2018 Aug 21];8:41. Available from: http://www.jidonline.com/text.asp?2018/8/1/41/226643



Sir,

I read with interest the case report by Arora et al. on the refractory mucormycosis resulting in maxillary necrosis in an Indian patient.[1] It is obvious that mucormycosis often occurs in immunocompromised individuals. Although the studied patient was immunodeficient by the underlying diabetes mellitus and hypothyroidism, I presume that the following immunodeficient condition ought to be concomitantly considered in the studied patient. Due to impaired immunity, individuals with human immunodeficiency virus (HIV) infection are susceptible to opportunistic infections more than individuals with a healthy immune system. Among these infections, mucormycosis has been reported in HIV-positive patients that has significant morbidity and mortality.[2] To my knowledge, HIV infection is a worrisome health issue in India. The current national HIV prevalence is 0.26% compared with a global average of 0.2%.[3] I presume that the rare occurrence of oral mucormycosis should alert the authors to define the HIV status of the studied patient. Hence, the arrangement for the diagnostic algorithm of CD4 count and viral overload measurements was solicited. If that diagnostic algorithm was done and it revealed underlying HIV infection, the case in question could be confidently considered a novel case report in India as HIV-associated maxillary mucormycosis has been rarely reported in the literature.[4]

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
   References Top

1.
Arora A, Patil BA, Adepu A, Reynold R. Refractory mucormycosis: A possible cause for maxillary necrosis. J Interdiscip Dent 2017;7:65-8.  Back to cited text no. 1
    
2.
Moreira J, Varon A, Galhardo MC, Santos F, Lyra M, Castro R, et al. The burden of mucormycosis in HIV-infected patients: A systematic review. J Infect 2016;73:181-8.  Back to cited text no. 2
    
3.
Paranjape RS, Challacombe SJ. HIV/AIDS in India: An overview of the Indian epidemic. Oral Dis 2016;22 Suppl 1:10-4.  Back to cited text no. 3
    
4.
Pedro-de-Lelis FJ, Sabater-Marco V, Herrera-Ballester A. Necrotizing maxillary sinus mucormycosis related to candidiasis and microsporidiosis in an AIDS patient. AIDS 1995;9:1386-8.  Back to cited text no. 4
    




 

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