J Interdiscip Dentistry
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INVITED REVIEW
Year : 2015  |  Volume : 5  |  Issue : 3  |  Page : 114-118

A conceptual framework (Cat-4) for estimating clinical relevance of evidence related to oral diagnosis


1 ARCPOH, School of Dentistry, University of Adelaide, Adelaide, SA, Australia; Department of Oral Sciences, School of Dentistry, National University of Singapore, Singapore
2 Dental Officer, Ministry of Health, Singapore

Correspondence Address:
Rahul Nair
ARCPOH, School of Dentistry, University of Adelaide, Adelaide, SA; Department of Oral Sciences, School of Dentistry, National University of Singapore

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2229-5194.181372

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This article categorizes studies that assess diagnosis in oral health care into four categories (Cat-4) based on the extent of clinically relevant information in its reported analyses. Category 1 includes studies publishing results from in vitro research. Category 2 includes studies that compare the test results of a diagnostic test of interest versus those of a reference test. Category 3 includes studies that assess the overall effect of the diagnostic test on future health, function, or quality of life. Finally, Category 4 includes studies that report economic analyses. Each category also includes a hierarchy of evidence (based on study design) that can be used for further assessment of internal validity along with other published criteria for testing internal validity and applicability. Clinical application of Cat-4 should result in greater awareness of the uncertainties in diagnosis that can result in missed diagnosis and overdiagnosis. CLINICAL RELEVANCE TO INTERDISCIPLINARY DENTISTRY
  • Quantification of the ultimate effects of diagnosis on a patientss' lives is needed
  • Cat-4 presents a framework that can combine clinical relevance and assessment of internal validity to evidence related to diagnosis
  • An understanding of the aspects of the evidence that are missing may result in a more realistic planning of clinical procedures.


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